Guide Attachment and detachment kinetics of FtsZ filaments
We have developed two different simulations, one to study the attachment of the filament after its collision with the inner membrane and the other to implement the slower reaction-diffusion process
Guide Mechanism of actin filament severing and capping by gelsolin
The authors use cryo-electron microscopy to reveal two structural states of Ca2+-activated gelsolin bound to the actin filament, illuminating the mechanisms of filament severing and
Guide Droplet detachment from a vertical filament with one end clamped
Understanding whether a droplet adheres to or detaches from a flexible filament upon axial impact is of significant interest, particularly in the context of raindrop impact on natural surfaces.
Guide 10.3 Muscle Fiber Contraction and Relaxation
It is one of several diseases collectively referred to as “muscular dystrophy.” DMD is caused by a lack of the protein dystrophin, which helps the thin filaments of myofibrils bind to the sarcolemma.
Guide Mechanisms of actin disassembly and turnover
Here, we review the molecular machinery and mechanisms employed in cells to drive the disassembly and turnover of actin networks.
Guide The actin filament pointed-end depolymerase Srv2/CAP
Here, using microfluidics-assisted three-color single-molecule imaging, we reveal that cyclase-associated protein (CAP), long known for its roles in nucleotide exchange and pointed-end
Guide Droplet detachment from a vertical filament with one end clamped
Here, we present an investigation into the detachment of droplets from an elastic filament clamped at one end and free at the other, initially oriented vertically.
Guide A proposed atomic model of the head-to-tail interaction in the filament
We propose and validate an atomic model of the head-to-tail (ACN) interaction of dimers that drives the longitudinal annealing of ULFs and short filaments into nascent IFs.
Guide Actin filament dynamics at barbed ends: New structures, new insights
We summarize recent biochemical and high-resolution structural studies that examine how actin filaments are regulated at their barbed ends by a diverse ensemble of proteins: formin, profilin,